論文
【2023年】
1.Influence of Immune System Abnormalities Caused by Maternal Immune Activation in the Postnatal Period
Yo Shimizu, Hiromi Sakata-Haga, Yutaka Saikawa and Toshihisa Hatta
Cells 2023, 12(5), 741
【2022年】
1.Hif1α-dependent hypoxia signaling contributes to the survival of deep-layer neurons and cortex formation in a mouse model.
Daisuke Sakai1, Takeru Sugawara, Tomonori Kurokawa, Yuki Murakami, Mitsuhiro Tomosugi, Hiroko Masuta, Hiromi Sakata‑Haga, Toshihisa Hatta and Hiroki Shoji
Molecular Brain volume 15, Article number: 28 (2022)
2.LIF–IGF Axis Contributes to the Proliferation of Neural Progenitor Cells in Developing Rat Cerebrum
Sho Takata, Hiromi Sakata-Haga, Hiroki Shimada, Tsuyoshi Tsukada, Daisuke Sakai, Hiroki Shoji, Mitsuhiro Tomosugi, Yuka Nakamura, Yasuhito Ishigaki, Hideaki Iizuka, Yasuhiko Hayashi and Toshihisa Hatta
【2021年】
1. Mid-pregnancy maternal immune activation increases Pax6-positive and Tbr2-positive neural progenitor cells and causes integrated stress response in the fetal brain in a mouse model of maternal viral infection.
Tsuyoshi Tsukada, Hiromi Sakata-Haga, Hiroki Shimada, Hiroki Shoji, Toshihisa Hatta
IBRO neuroscience reports 11:73-80, 2021
2. Cerebrospinal fluid may flow out from the brain through the frontal skull base and choroid plexus: a gold colloid and cadaverine injection study in mouse fetus.
Akai, Takuya, Toshihisa Hatta, Hiromi Sakata‐Haga, Seiji Yamamoto, Hiroki Otani, Shusuke Yamamoto and Satoshi Kuroda. Child's Nervous System 1 – 8, 2021.
3. Decidual cells are the initial target of polyriboinosinic-polyribocytidylic acid in a mouse model of maternal viral infection.
Tsuyoshi Tsukada, Hiroki Shimada, Hiromi Sakata-Haga, Hiroki Shoji, Hideaki Iizuka, Toshihisa Hatta
Biochemistry and biophysics reports 26:100958-100958, 2021
4. Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health.
Joji Kusuyama, Ana Barbara Alves-Wagner, Royce H Conlin, Nathan S Makarewicz, Brent G Albertson, Noah B Prince, Shio Kobayashi, Chisayo Kozuka, Magnus Møller, Mette Bjerre, Jens Fuglsang, Emily Miele, Roeland J W Middelbeek, Yang Xiudong, Yang Xia, Léa Garneau, Jayonta Bhattacharjee, Céline Aguer, Mary Elizabeth Patti, Michael F Hirshman, Niels Jessen, Toshihisa Hatta, Per Glud Ovesen, Kristi B Adamo, Eva Nozik-Grayck, Laurie J Goodyear
Cell metabolism 33(5): 939-956, 2021
5. Melanocortin 5 receptor contributes to sensitivity to UV-B waves and barrier function in mouse epidermis
Akari Shintani, Hiromi Sakata-Haga, Keiichi Moriguchi, Mitsuhiro Tomosugi, Daisuke Sakai, Tsuyoshi Tsukada, Makoto Taniguchi, Masahide Asano, Hiroki Shimada, Hiroki Otani, Hiroki Shoji, Junko Hatta, Takashi Mochizuki, Toshihisa Hatta
JID Innovations 100024-100024, 2021
6. Rapid bone staining with hair removal (RAP-B/HR): a non-destructive and rapid whole-mount bone staining protocol optimized for adult hairy mice.
Nobuo Kariyama, Hiromi Sakata-Haga, Tsuyoshi Tsukada, Hiroki Shimada, Makoto Taniguchi, Toshihisa Hatta
Scientific reports 11(1): 1950-1950, 2021
7. Leukemia Inhibitory Factor Induces Proopiomelanocortin via CRH/CRHR Pathway in Mouse Trophoblast.
He Wang, Hiromi Sakata-Haga, Hiroko Masuta, Mitsuhiro Tomosugi, Tsuyoshi Tsukada, Hiroki Shimada, Daisuke Sakai, Hiroki Shoji, Toshihisa Hatta
Frontiers in cell and developmental biology 9: 618947-618947, 2021
8. Exposure to Maternal Immune Activation Causes Congenital Unfolded Protein Response Defects and Increases the Susceptibility to Postnatal Inflammatory Stimulation in Offspring.
Yo Shimizu, Tsuyoshi Tsukada, Hiromi Sakata-Haga, Daisuke Sakai, Hiroki Shoji, Yutaka Saikawa, Toshihisa Hatta
Journal of inflammation research 14: 355-365, 2021
【2020年】
1. Wang H, Tsukada T, Shimada H, Sakata-Haga H, Iida Y, Zhang S, Shoji H, Hatta T.: Leukemia inhibitory factor induces corticotropin-releasing hormone in mouse trophoblast stem cells, Biochem Biophys Res Commun. 2020 Jan 29;522(1):81-87. doi: 10.1016/j.bbrc.2019.11.059. Epub 2019 Nov 15.
2. Yamada K, Shiga H, Noda T, Harita M, Ishikura T, Nakamura Y, Hatta T, Sakata-Haga H, Shimada H, Miwa T.: The impact of ovariectomy on olfactory neuron regeneration in mice, Chem Senses. 2020 Feb 3. pii: bjaa005. doi: 10.1093/chemse/bjaa005. Epub 2020 February 03.
【2019年】
1．Tsukada T, Shimada H, Sakata-Haga H, Iizuka H, Hatta T.: Molecular mechanisms underlying the models of neurodevelopmental disorders in maternal immune activation relevant to the placenta. Congenital Anomalies, 2019, 59(3):81-87, doi:org/101111/cga.12323.（総説）
2. 坂田ひろみ、八田稔久：病理形態学の新技術「臓器の透明化の原理と実際」、病理と臨床 37（7）：588-594 2019
3. Matsuda K, Kitahara T, Ito T, Fukushima M, Fukuda J, Sato G, Kitamura Y, Abe K, Uno A, Tomita K, Sakata-Haga H, Fukui Y, Takeda N.： A new immunohistochemical method to evaluate the development of vestibular compensation after unilateral labyrinthectomy in rats, Acta Oto-Laryngologica, 2019 Jun;139(6):505-510. doi: 10.1080/00016489.2019.1599140. Epub 2019 Apr 16.
4. Noda T, Shiga H, Yamada K, Narita M, Nakamura Y, Ishikur T, Kumai M, Kawakami Z, Kaneko A, Hatta T, Sakata-Haga H, Shimada H, Miwa T.: Effects of tokishakuyakusan on regeneraon of murine olfactory neurons In vivo and In vitro, Chemical Senses, 2019,06,44(5):327-338. doi: 10.1093/chemse/bjz023
【2018年】
1． Sakata-Haga H, Uchishiba M, Shimada H, Tsukada T, Mitani M, Arikawa T, Shoji H, Hatta T.: A rapid and nondestructive protocol for whole-mount bone staining of small fish and Xenopus, SCIENTIFIC REPORTS 2018.05 10.1038/s41598-018-25836-4
2. Bold J, Sakata-Haga H, Fukui Y: Spinal nerve defects in mouse embryos prenatally exposed to valproic acid. anatomical science international 93：35-41
10.1007/s12565-016-0363-9. 2018
3. Yoshihara T, Satake H, Nishie T, Okino N, Hatta T, Otani H, Naruse C, Suzuki H, Sugihara K, Kamimura E, Tokuda N, Furukawa K, Fururkawa K, Ito M, Asano M: Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice PLOS Genetics https://doi.org/10.1371/journal.pgen.1007545 Published: August 16, 2018
【2017年】
1． Akai1 T, Hatta T, Shimada H, Mizuki K, Kudo N, Hatta T, Otani H: Extracranial outflow of particles solved in cerebrospinal fluid: Fluorescein injection study Congenital Anomalies 2017 10.1111/cga.12257
2. Yoshitomi Y, Ikeda T, Saito H, Yoshitake Y, Ishigaki Y, Hatta T, Kato N, Yonekura H.: JunB regulates angiogenesis and neurovascular parallel alignment in mouse enbryonic skin Journal of Cell Science 130: 916-926 2017 10.1242/jcs.196303
【2016年】
1． Arikawa T, Shengjun Liao, Shimada H, Inoue T, Sakata-Haga H, Nakamura T, Hatta T Shoji H.: Galectin-4 expression is down-regulated in response to autophagy during differentiation of rat trophoblast cells, Scientific Reports 6, Article number: 32248 (2016) doi:10.1038/srep32248
2. 八田稔久：神経管の発生 小児の脳神経 41: 296─303, 2016
3. 八田稔久、三谷真弓： 生物試料の透明化：古典から最新技術まで． 医生電顕技術雑誌 29：54-56 2016
【2015年】
1. Nonaka Y, Ogawa T, Yoshida H, Shoji H, Nishi N, Kamitori S, Nakamura T.: Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-1. Glycobiology. 25(7):792-803. 2015
2. Tsukada T, Simamura E, Shimada H, Arai T, Higashi N, Akai T, Iizuka H and Hatta T: The suppression of maternal-fetal leukemia inhibitory factor signal relay pathway by maternal immune activation impairs brain development in mice. PLOS ONE. 2015 Jun 4;10(6):e0129011. doi: 10.1371/journal.pone.0129011
3. Simamura E, Arikawa T, Ikeda T, Shimada H, Shoji H, Masuta H, Nakajima Y, Otani H, Yonekura H, Hatta T.: Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5. PLOS ONE. 2015 Apr 10(4):1-17. doi: 10.1371/journal.pone.0123232
4. Nakata H, Wakayama T, Sonomura T, Honma S, Hatta T, Iseki S.: Three-dimensional structure of seminiferous tubules in the adult mouse. J. Anat, doi: 10.1111/joa.12375 2015 227:5;686-694
【2014年】
1. Inoue T, Hashimoto R, Matsumoto A, Jahan E, Rafiq AM, Udagawa J, Hatta T, Otani H.: In vivo analysis of Arg-Gly-Asp sequence/integrin α5β1-mediated signal involvement in embryonic enchondral ossification by exo utero development system. J Bone Miner Res. 2014, 29(7):1554- 1563. doi: 10.1002/jbmr.2166.
2. Arikawa T, Simamura E, Shimada H, Nakamura T, Hatta T, Shoji H.: Significance of sugar chain recognition by galectins and its involvement in disease-associated glycosylation. (Review) Congenital Anomalies, 2014, 54(2):77-81, doi:10.1111/cga.12055.
【2013年】
1. Hattori T, Arikawa T, Fujioka Y, Maruyama J, Nakayama Y, Ohba Y, Niki T, Miyazaki T, Hirashima M, Kida H.: Inhibition of influenza A infection by galectin-9. Japanese Journal of Veterinary Research, 2013; 61(1&2); 5-18
【2012年】
1. Yamada M, Udagawa J, Hashimato R, Matsumoto A, Hatta T, Otani H.: Interkinetic nuclear migration during early development of midgut and ureteric epithelia. Anat Sci Int. 88: 31-37 2012 doi: 10.1007/ｓ12565-012-0156-8
2. Arikawa T, Simamura E, Shimada H, Nishi N, Tatsuno T, Ishigaki Y, Tomosugi N, Yamashiro C, Hata T, Takegami T, Mogami H, Yamaguchi K, Nakamura T, Otani H, Hatta T, Shoji H.: Expression pattern of Galectin 4 in rat placentation. Placenta 33: 885-887 2012 doi:10.1016/ｊ.placenta.2012.07.013
【2011年】
1. Simamura E, Shimada H, Shoji H, Otani H, Hatta T.: Effects of melanocortins on fetal development. Congenit Anom(Kyoto) 51: 47-54 2011
2. Hashimoto R, Udagawa J, Kagohashi Y, Matsumoto A, Hatta T, Otani H.: Direct and indirect effects of neuropeptide Y and neurotrophin 3 on myelination in the neonatal brains. Brain Res. 1373: 55-66 2011 DOI: 10.1016/j.brainres.2010.12.027
【2010年】
1. Hatta J, Hatta T, Miyagawa S, Kitahara Y, Hirota T, Anzawa K, Mochizuki T.: Quantitative analysis of the effects of antimycotic agents on the hyphal growth of Trichophyton rubrum: a preliminary study. Mycoses. Mycoses 54: e84- e91, 2010
2. Simamura E, Shimada H, Higashi N, Uchishiba M, Otani H, Hatta T.: Maternal leukemia inhibitory factor (LIF) promotes fetal neurogenesis via a LIF-ACTH-LIF signaling relay pathway. Endocrinology 151: 1853-1862 2010.4 DOI: 10.1210/en.2009-0985
3. Yamada M, Udagawa J, Matsumoto A, Hashimoto R, Hatta T, Nishida M, Minami Y, Otani H.: Ror2 is required for midgut elongation during mouse development. Dev Dynam 239: 941-953 2010 DOI: 10.1002/dvdy.22212
4. Otani H, Udagawa J, Hatta T, Kagohashi Y, Hashimoto R, Matsumoto A, Satow F, Nimura M.: Individual variation in organ histogenesis as a causative factor in the developmental origins of health and disease: unnoticed congenital anomalies? Congenit Anom(Kyoto) 50: 205-211 2010
【2009年】
1. Shimada H, Hirai K-I, Simamura E, Hatta T, Iwakiri H, Mizuki K, Hatta T, Sawasaki T, Matsunaga S, Endo Y, Shimizu S.: Paraquat toxicity induced by voltage-dependent anion channel 1 acts as an NADH-dependent oxidoreductase. J Biol Chem 284: 28642-28649 2009
2. Daisu M, Hatta T, Sakurai-Yamashita Y, Nabika T, Moritake K.: Quantitative analysis of delayed neuronal death in the hippocampal subfields of SHRSP and SHR Cell Mol Neurobiol 29: 557-562 2009
3. 東 伸明, 島田ひろき,島村英理子,八田稔久: 左胃動脈、脾動脈、総肝動脈が共同幹となす腹腔動脈の分枝様式. 解剖誌 84: 7-10, 2009.3
4. Fukazawa I, Hatta T, Uchio Y, Otani H.: Development of the meniscus of the knee joint in human fetuscs. Congenit Anom(Kyoto) 49: 27-32 2009
【2008年】
1. Otani H, Udagawa J, T. Lundh, Hatta T, Hashimoto R, Matsumoto A, Satow F.: Morphometric study on the characteristic external features of normal and abnormal human embryos. Congenit Anom(Kyoto) 48: 18-28 2008
2. Simamura E, Shimada H, Ishigaki Y, Hatta T, Higashi N, Hirai K-I.: Bioreductive activation of quinone antitumor drugs by mitochondrial voltage-dependent anion channel 1. Anat. Sci. Int 83: 261-266 2008.8
3. Simamura E, Shimada H, Hatta T, Hirai K-I.: Mitochondrial voltage-dependent anion channels (VDACs) as novel pharmacological targets for anti-cancer agents. J. Bioenerg. Biomembr 40: 213-217 2008
4. Kaneyama K, Segami N, Hatta T.: Congenital deformities and developmental abnormalities of the mandibular condyle in the temporomandibular joint. Congenit Anom(Kyoto) 48: 118-125 2008
5. Higashi N, Shimada H, Simamura E, Hatta T.: Right vertebral artery as the fourth branch of the aortic arch. Anat. Sci. Int 83: 314-318 2008.8
6. Yamada M, Hatta T Otani H.: Mouse exo utero development system; Protocol and troubleshooting. Congenit Anom(Kyoto) 48: 183-187 2008
7. Nakamura K, Ichise H, Nakao K, Hatta T, Otani H, Sakagami H, Kondo H, Katsuki M.: Partial functional overlap of the three ras genes in mouse embryonic development. Oncogene 27: 2961-2968 2008
【2007年】
1. Habib H, Hatta T, O. I. F. Rahman, Yoshimura Y, Otani H.: Fetal jaw movement affects development of articular disk in the temporomandibular joint. Congenit Anom(Kyoto) 47: 53-57 2007
2. Hatta T, Satow F, Hatta J, Hashimoto R, Udagawa J, Matsumoto A, Otani H.: Development of the Pons in Human Fetuses.: Congenit Anom(Kyoto) 47: 63-67 2007
3. Udagawa J, Hatta T, Hashimoto Otani H.: Roles of leptin in prenatal and perinatal brain development.: Congenit Anom(Kyoto) 47: 77-83 2007
4. 八田稔久, 山田真紀子, 島村英理子, 島田ひろき, 二村正行, 松本暁洋, 宇田川 潤, 橋本龍樹, 東 伸明, 大谷 浩：マウス胎児子宮外発生法，金医大誌 32(1): 16-22，2007．6
【2006年】
1. Udagawa J, Hashimoto R, Suzuki H, Hatta T, Sotomaru Y, Hioki K, Kagohashi Y, Nomura T, Minami Y, Otani H.: The role of leptin in the development of the cerebral cortex in mouse embryos.: Endocrinology 147: 647-658 2006
2. Nimura M, Udagawa J, Hatta T, Hashimoto R, Otani H.: Spatial and temporal patterns of expression of melanocortin type 2 and 5 receptors in the fetal mouse tissues and organs. Anat Embryol 211: 109-117 2006
3. Hatta J, Hatta T, Moritake K, Otani H.: Heavy water inhibiting the expression of transforming growth factor-1 and the development of kaolin-induced hydrocephalus in mice. J Neurosurg (4 Suppl Pediatrics) 104: 251-258 2006
4. Hatta T, Matsumoto A, Ono A, Udagawa J, Nimura M, Hashimoto R, Otani H.: Quantitative analyses of leukemia inhibitory factor in the cerebrospinal fluid in mouse embryos. Neuroreport 17: 1863-1866 2006
5. Chou SJ, Hermesz E, Hatta T, Feltner D, El-Hodiri HM, Jamrich M, Mahon K.: Conserved regulatory elements establish the dynamic expression of Rpx/HesxI in early vertebrate development.: Dev Biol 292: 533-545 2006
6. Simamura E, Hirai K, Shimada H, Koyama J, Shimizu S.: Furanonaphthoquinones cause apoptosis of cancer cells by inducing the production of reactive oxygen species by the mitochondrial voltage-dependent anion channel. Cancer Biol Ther, 5(11): 1523-1529 2006
7. Koyama J, Morita I, Kobayashi N, Hirai K, Simamura E, Nobukawa T, Kadota S.: Antiallergic activity of aqueous extracts and constituents of Taxus yunnanensis. Biol Pharm Bull 29(11), 2310-2312 2006
8. Ueda JY, Awale S, Tezuka Y, Shimamura E, Hirai K-I, Nobukawa T, Sato A, Kadota S.: Growth inhibitory activity of wood of Taxus yunnanensis and its liquid chromatography Fourier-transform mass spectrometry analysis. Biol Planta Med 72(13) , 1241-1244 2006
【2005年】
1. Habib H, Hatta T, Udagawa J, Zhang L, Yoshimura Y, Otani H.: Fetal jaw movement affects condylar cartilage development. J Dent Res 84: 474-479 2005.
2. Desmond JC, Kawabata H, Mueller-Tidow C, Simamura E, D.Heber, K.Hirai, H.P.Koeffler.: The synthetic furanonaphthoquinone induces growth arrest, apoptosis and differentiation in a variety of leukaemias and multiple myeloma cells. British Journal of Haematology 131:520-529 2005.
【2004年】
1. Hatta T, Matsumoto A, Otani H.: Application of the mouse exo utero development system in the study of developmental biology and teratology.: Congenit Anom(Kyoto) 44: 2-8 2004.
【2003年】
1. Hatta T, Matsumoto A, Moriyama K, Otani H.: Opposite effects of the maternal immune system activated by interleukin-1 vs. PSK and OK432 on 5-azacytidine-induced birth defects. Congenit Anom(Kyoto) 43: 46-56 2003.
2. Simamura E, Hirai K-I, Shimada H, Pan J, Koyama J.: Mitochondrial damage prior to apoptosis in furanonaphthoquinone treated lung cancer cells. Cancer Detection and Prevention 27: 5-13 2003.
【2002年】
1. Hatta T, Moriyama K, Nakashima K, Taga T, Otani H.: The role of gp130 in cerebral cortical development: in vivo functional analysis in a mouse exo utero system. J Neurosci 22: 5516-5524 2002.
3. Matsumoto A, Hatta T, Moriyama K, Otani H.: Sequential observation of exencephaly and subsequent morphological changes by mouse exo utero development system: analysis of the mechanism of transformation from exencephaly to anencephaly. Anat Embryol 205: 7-18 2002.
4. Shimada H, Furuno H, Hirai K-I, Koyama J, Ariyama J, Simamura E.:Paraquat detoxicative system in the mouse liver postmitochondrial fraction. Archives of Biochemistry and Biophysics, 402: 149-157, 2002.
5. Kuroyanagi M, Shimamura E, Kim M, Arakawa N, Fujiwara Y, Otsuka M.: Effects of L-ascorbic acid on lysyl oxidase in the formation of collagen cross-links. Bioscience Biotechnology and Biochemistry, 66(10): 2077-2082, 2002.
6. 金丸聡人, 島村英理子, 小山淳子: ダイオキシンの急性細胞毒性における活性酸素の生成とα-トコフェロールによる防御. 金沢医科大雑誌 27: 122-129, 2002.
7. Hirai K-I, Pan J, Shui Y.B, Simamura E, Shimada H, Kanamaru T, Koyama J,: Alpha-tocopherol protects cultured human cells from the acute lethal cytotoxicity of dioxin. International Journal of Vitamin and Nutrition Research, 72: 147-153, 2002.
【2001年】
1. Udagawa J, Hatta T, Naora H, Hashimoto R, Tashiro M, Tanaka O, Otani H.: Change in hair cycle and hair length in nude mice by administration of deuterium oxide.: Biol Rhythm Res 32: 73-84 2001.
2. Simamua E, Hirai K-I, Shimada H, Koyama J.: Apoptosis and epithelial phagocytosis in mitomycin C-treated human pulmonary adenocarcinoma A549 cells. Tissue and Cell, 33: 161-168, 2001.
3. Simamura E, Shimada H, Hirai K-I.: Reactive oxygen species produced in the mitochondria of human cancer cells by furanonaphthoquinones that induce apoptosis: Energy-filter analytical electron microscopy. Acta Histochemica et Cytochemica, 34: 43, 2001.
【2000年】
1. Zhang H, Ma Lang, Hatta T, Otani H.: Fetal-maternal adrenocortical activities approaching parturition in mice. Shimane J. Med. Sci. 18: 5-9 2000.
2. L. Zhang, Yoshimura Y, Hatta T, Otani H.: Reconstructing the pathway of the tensor veli palatini motor nerve during early mouse development. Anat. Embryol. 201: 235-244 2000.
3. Udagawa J, Hatta T, Naora H, Otani H.: Expression of the long form of leptin receptor (Ob-Rb) mRNA in the brain of mouse embryos and newborn mice. Brain Res 868: 251-258 2000.
4. Takeuchi S, Takeda K, Oishi I, Nomi M, Ikeya M, Itoh K, Tamura S, Ueda T, Hatta T, Otani H, Terashima T, Takada S, Yamamura H, Akira S, Minami Y.: Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation.: Genes Cells 5: 71-78 2000/
5. Ariyama J, Shimada H, Aono M, Tsuchida H, Hirai K-I.: Propofol improves recovery from paraquat acute toxicity in vitro and in vivoIntensive Care Med, 26: 981-987, 2000.
6. Pan J, Simamura E, Koyama J, Shimada H, Hirai K-I.: Induced apoptosis and necrosis by 2-methylfuranonaphthoquinone in human cervical cancer HeLa cells. Cancer Detection and Prevention. 24: 266-274, 2000.
【1999年】
1. Nishiki M, Murakami y, Kawaguchi M, Hashimoto R, Hatta T, Otani H, Kanatsu K, Kajiwara H, Osamura Y, Kato Y.: Renal expression of insulin-like growth factor-1 in acute renal failure: a preliminary report.: Clin Nephrol 52:148-151 1999.
2. Zhang L, Yoshimura Y, Hatta T, Otani H.: Myogenic determination and differentiation of the mouse palatal muscle in relation to the developing mandibular nerve. J Dent Res 78: 1417-1425 1999.
3. Zhang H, L. Ma, Matsumoto A, Hatta T, Otani H.: Morphological traits, cell proliferation and apoptosis in adrenocortical X-zone in pregnant mice. Shimane J. Med. Sci. 17: 19-23 1999.
4. Nishikori T, Hatta T Kawauchi H, Otani H.: Apoptosis during inner ear development in human and mouse embryos: an analysis by computer-assisted three-dimensional reconstruction. Anat. Embryol. 200: 19-26 1999.
5. Zhang H, Hatta T, L. Ma, Hashimoto R, Kihara I, Otani H.: Acute in vivo effects of ACTH by exo utero microinjection on differentiation, steroidogenesis and proliferation of fetal mouse adrenocytes.: Endocr Res 25: 51-66 1999.
6. Oishi I, Takeuchi S, Hashimoto R, Nagabukuro A, Ueda T, Zhao-Jun Liu, Hatta T, Akira S Matsuda Y, Yamamura H, Otani H, Minami Y.: Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: Implications in development and function of the nervous system.: Genes Cells 4: 41-56 1999.
7. Hirai K-I, Pan J, Shimada H, Izuhara T, Kurihara T, Moriguchi K.: Cytochemical energy- filtering transmission electron microscopy of mitochondrial free radical formation in paraquat cytotoxicity J Electron Microsc, 48 : 289-296, 1999.
8. Hirai K-I, Shimada H, Pan J, Katoh S, Simamura E.: Mitochondrial NADH-quinone oxidoreductase (NQOm) produces reactive oxygen species in the chemical injury of rat liver mitochondria. Acta Histochem Cytochem, 32: 239-242, 1999.
9. Hirai K-I, Koyama J, Pan J, Simamura E, Shimada H, Yamori T, Sato S, Tagahara K, Tsuruo T.: Furanonaphthoquinone analogs possessing preferential antitumor activity compared to normal cells. Cancer Detection and Prevention. 23: 539-550, 1999.
【1998年】
1. Zhang H, Hatta T, Udagawa J, L. Ma, Naora H, Hashimoto R, Otani H.: Fetal adrenocortex-medulla interactions and changes of pituitary in mouse embryos with an ectopic corticotrophic tumor.: Endocr Res 24: 947-951 1998.
2. Zhang H, Hatta T, Udagawa J, Moriyama Hashimoto K R, Otani H.: Induction of ectopic corticotropic tumor in mouse embryos by exo utero cell transplantation and its effects on the fetal adrenal gland.: Endocrinology 139: 3306-3315 1998.
3. Hatta J, Hatta T, Otani H, Moritake K.: Deuterium oxide inhibits the development of kaolin-induced hydrocephalus in mice. Jpn J Deuterium Sci 7: 25-29 1998.
4. Matsuda S, Mishima K, Yoshimura Y, Hatta T, Otani H.: Apoptosis in the development of the temporomandibular joint.: Anat. Embryol. 196: 383-391 1997
5. Shimada H, Hirai K-I, Simamura E, Pan J.: Mitochondrial NADH-quinone oxidoreductase of the outer membrane is responsible for paraquat cytotoxicity in rat livers. Arch Biochem Biophys 351: 75-81, 1998.
6. Takegami T, Simamura E, Hirai K-I, Koyama J.: Inhibitory effect of furanonaphthoquinone derivatives on the replication of Japanese encephalitis virus. Antiviral Research. 37: 37-45, 1998.
7. Kim M, Otsuka M, Shimamura E, Arakawa N.: The effect of L-ascorbic acid on age-related changes of pyridinoline in cartilage collagen of guinea pigs. Journal Nutritional Science and Vitaminology (Tokyo) 44: 217-224 1998
【1997年】
1. Koera K, Nakamura K, Nakao K, Miyoshi J, Toyoshima K, Hatta T, Otani H, Aiba A, Katsuki M.: Ras is essential for the development of the mouse embryo. Oncogene 15: 1151-1159 1997.
2. Hatta J, Hatta T, Takamura M, Moritake K, Otani H.: Experimental hydrocephalus: history of animal models and the application of deuterium oxide to treatment. Jpn J Deuterium Sci 6: 13-19 1997.
3. Sekimoto H, Hatta T, Moriyama K, Otani H, Moritake K, Tanaka O.: Developmental analysis of chlorambucil-induced occipital blebs in mice. Congenit Anom(Kyoto). 37: 31-45 1997.
4. Pan J, Hirai K-I, Simamura E, Koyama J, Shimada H, Kuwabara S.: Mitochondrial damage by a new antitumour agent furanonaphthoquinone derivative inhuman cervical cancer HeLa cells. Journal of Electron Microscopy Tokyo.46: 181-187, 1997.
5. 平井圭一, 潘杰紅, 島田ひろき, 島村英理子, 東田紀彦: 不安定酵素反応保存のための固定法. 電子顕微鏡, 32: 173-175, 1997.
6. 高島雅之, 島村英理子, 友田幸一: ヒト舌癌細胞に対するフラノナフトキノン誘導体の抗癌作用. 金沢医科大雑誌, 22: 368-376, 1997.
7. 潘杰紅, 平井圭一, 島村英理子: フラノナフトキノン誘導体によるヒト子宮頸癌細胞に対する抗腫瘍作用. 金沢医科大雑誌, 22: 213-223, 1997.
【1996年】
1. Hatta T, Otani H, Tanaka O.: In vivo analysis of RGD-sequence dependent cortical histogenesis in mouse telencephalon. Shimane J. Med. Sci. 14: 1-6 1995/96.
2. Udagawa J, Hatta T, Naora H, Hashimoto R, Otani H.: Effects of deuterium oxide on the hair growth.: J Deuterium Sci 5巻, p.15-21 1996.
3. 堀口章子, 島村英理子.: ヒト喉頭癌細胞に対するフラノナフトキノン誘導体の効果. 金沢医科大雑誌, 21: 462-471, 1996.
【1995年】
1. Matsubara K, Kobayashi S, Kobayashi Y, Yamashita K, Koide H, Hatta T, Iwamoto K, Tanaka O, Kimura K.: -Carbolinium cations, endogenous MPP+ analogs, in the lumbar cerebrospinal fluid of patients with Parkinson's disease. Neurology 45: 2240-2245 1995.
【1994年】
1. Hatta T, Tanaka O, Otani H.: Contribution of RGD sequence to neuronal migration in developing cerebral cortex. Neuroreport 5: 2261-2264 1994.
2. Oguni M, Setogawa T, Otani H, Hatta T, Tanaka O.: Development of the lens in human embryos: A histochemical and ultrastructural study. Acta Anat 149巻, p.31-38 1994.
【1993年】
1. Otani H, Yoneyama T, Hashimoto R, Hatta T, Tanaka O.: UItrastructure of the developing stomach in human embryos. Anat Embryol 187: 145-151 1993.
【1991年】
1. Tanaka O, Yoshioka N, Yoshioka T, Otani H, Hatta T, Hashimoto R A. Abu-Musa.: Effects of chlorambucil on the brain development in mice during post-neurulation period.: Congenit Anom(Kyoto). 31: 141-152 1991.
2. Yoshioka T, Sekimoto H, Hatta T, Hashimoto, Tanaka O.: Extralysosomal localization of acid para-nitrophenylphosphatase activity int he developing rat cerebellar cortex. Acta Histochem. Cytochem. 24: 241-249 1991.
【1990年】
1. Shinohara H, Naora H, Hashimoto R, Hatta T, Tanaka O.: Development of the innervation pattern in the upper limb of staged human embryos. Acta Anat 138巻, p.265-269 1990.
2. Tanaka O, Yoshioka N, Yoshioka T, Naora H, Hatta T.: Morphological analysis of neural tube defects: Chlorambucil-induced exencephaly in mice. Congenit Anom(Kyoto) 30: 5-16 1990.